Indications of Tolson
Treatment of painful musculoskeletal disorders with hypermyotonia and decreased motility, especially those resulting from spinal cord injuries, osteoporosis, arthritis, and spasticity. It has also been effective in lumboischial pain, neurolathyrism, knee arthritis, peripheral circulatory diseases, climacteric muscular and vascular complaints, trismus, myogenous headaches, rheumatic diseases accompanied by muscular hypertonia, spasms, pain, inflammatory symptoms and limited motion, and in the post-surgical treatment of traumatologic patients.
Central Depolarizing muscle relaxants, Centrally acting Skeletal Muscle Relaxants
Tolson – Tolperisone Hydrochloride is a centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm. It effectively reduces muscular hypertonicity, improves peripheral blood flow by vasodilatation and reduces pain
Tolson – Tolperisone is a centrally acting muscle relaxant that acts at the reticular formation in the brain stem by blocking voltage-gated sodium and calcium channels
Dosage & Administration
Adult: 150-450 mg daily, administered in 2 or 3 divided doses. The maximum dosage is 450 mg/day.
3 months to 6 years: 1-2 mg/kg/day in 3 divided doses.
6 years to 14 years: 2-4 mg/kg/day in 3 divided doses
Concomitant use of Methocarbamol with Tolperisone Hydrochloride has been reported to cause disturbance of visual accommodation.
Hypersensitivity, Myasthenia Gravis and nursing mother.
Diarrhea, dizziness, drowsiness, dryness of the mouth, fall of blood pressure, fatigue, gastric complaints, headaches, hypersensitivity, itching, muscle pain, muscle weakness, rash, and somnolence.
Pregnancy & Lactation
Tolson – Tolperisone Hydrochloride should be used in pregnancy according to physician’s advice. Tolperisone hydrochloride should not be used during breast-feeding.
In case of children, the prescribed dose and duration of treatment should closely be observed.
Excitability has been noted after ingestion of high doses by children. In suicide studies of three isolated cases, it is believed that ingestion of tolperisone was the cause of death.
Tolson – Tolperisone Hydrochloride should be stored below 30° C. Keep out of reach of children
If you need any assistance/consultation, please do not hesitate to contact us.