Ribox 120 Tablet

Beximco Pharmaceuticals Ltd
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Ribox Tablet
Etoricoxib
120 mg

Indicated For

Etoricoxib is indicated for relief of pain and inflammation in-

  • Osteoarthritis
  • Rheumatoid arthritis
  • Other chronic musculoskeletal disorders
  • Acute gout
  • Dysmenorrhoea
  • Following dental surgery

৳ 13.99

In stock

Indications for Ribox 120

Etoricoxib is indicated for relief of pain and inflammation in-

  • Osteoarthritis
  • Rheumatoid arthritis
  • Other chronic musculoskeletal disorders
  • Acute gout
  • Dysmenorrhoea
  • Following dental surgery

Therapeutic Class
Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Pharmacology
Ribox 120- Etoricoxib is a non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, and antipyretic activities. Etoricoxib is a potent, orally active & highly selective cyclooxygenase-2 (COX-2) inhibitor. COX-2 is primarily responsible for the synthesis of prostanoid mediators of pain, inflammation and fever. Etoricoxib decreases these clinical signs and symptoms effectively with decreased GI toxicity. Moreover it has no effect on platelet function.

Dosage & Administration
The recommended dose for adult and patient over 16 years:
Acute pain: 120 mg once daily. Ribox 120- Etoricoxib 120 mg should be used only for acute symptomatic period, limited to a maximum of 8 days treatment.
Chronic musculoskeletal pain: 60 mg once daily.
Osteoarthritis: 30 mg once daily, increased if necessary to 60 mg once daily.
Rheumatoid arthritis and ankylosing spondylitis: 90 mg once daily.
Acute gout: 120 mg once daily for max. 8 days. Max. 60 mg daily in mild hepatic impairment; max. 60 mg on alternate days or 30 mg once daily in moderate hepatic impairment.

Interaction
Oral anticoagulants, diuretics and ACE inhibitors, Acetylsalicylic acid, Cyclosporin and Tacrolimus, Lithium, Methotrexate, oral contraceptives, Prednisone/Prednisolone, Digoxin, drugs metabolized by sulfotransferases (Ethinyl Estradiol), drugs metabolized by CYP isoenzymes, Ketoconazole, Rifampicin, and Antacids have interaction with Etoricoxib.

Contraindications
It is contraindicated in patients with hypersensitivity to Ribox 120- Etoricoxib or any component of this product, congestive heart failure, patients with inflammatory bowel disease, severe hepatic dysfunction.

Side Effects
Dry mouth, taste disturbance, mouth ulcer, flatulence, constipation, appetite and weight changes, chest pain , fatigue, paraesthesia, influenza like syndrome, myalgia etc. may occur.

Pregnancy & Lactation
As with other drugs known to inhibit Ribox 120- prostaglandin synthesis, use of it should be avoided in late pregnancy because it may cause premature closure of the ductus arteriosus. It should be used during the first two trimesters of pregnancy only if
the potential benefit justifies the potential risk to the foetus. It is not known whether this drug is excreted in human milk.

Precautions
A patient with decreased liver & kidney function, dehydration, hypertension, heart failure, GI perforation & patients over 65 years of age. Use in Pregnancy and Lactation As with other drugs known to inhibit prostaglandin synthesis, use of it should be avoided in late pregnancy because it may cause premature closure of the ductus arteriosus. It should be used during the first two trimesters of pregnancy only if the potential benefit justifies the potential risk to the foetus. It is not known whether this drug is excreted in human milk.

Overdose Effects
Symptoms: GI and cardiorenal events.

Management: Symptomatic and supportive treatment. Remove unabsorbed material from the GI tract.

Storage Conditions
Store at a cool & dry place protected from light & moisture. Keep out of reach of children.

If you need any assistance/consultation, please do not hesitate to contact us.

SKU: O-RIBO-BEX-120 Category:
Weight 0.012 g
Drug Manufacturer

Form Of Drug

Tablet

Generic Names

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