Gabapen 100 Tablet

Incepta Pharmaceuticals Ltd
Availability:

In stock


Compare

Gabapen Tablet
Gabapentin
100 mg
Incepta Pharmaceuticals Limited

Indications

Gabapentin is indicated for-

  • Epilepsy
  • Neuropathic pain (e.g. postherpetic neuralgia) and other pain conditions
  • Bipolar disorder
  • Headache syndrome
  • Spasticity in multiple sclerosis and spinal cord diseases

Others indication are:

  • Alcohol withdrawal
  • Schizoaffective disorder
  • Post-traumatic stress disorder
  • Agitation and behavioural disturbances
  • associated with dementia
  • Lesch-Nyhan syndrome
  • Essential tremor
  • Restless legs syndrome
  • Brachioradial pruritus
  • Hemichorea/hemiballismus
  • Hot Flashes

৳ 6.00

In stock

Indications

Gabapen 100 – Gabapentin is indicated for-

  • Epilepsy
  • Neuropathic pain (e.g. postherpetic neuralgia) and other pain conditions
  • Bipolar disorder
  • Headache syndrome
  • Spasticity in multiple sclerosis and spinal cord diseases

Others indication are:

  • Alcohol withdrawal
  • Schizoaffective disorder
  • Post-traumatic stress disorder
  • Agitation and behavioural disturbances
  • associated with dementia
  • Lesch-Nyhan syndrome
  • Essential tremor
  • Restless legs syndrome
  • Brachioradial pruritus
  • Hemichorea/hemiballismus
  • Hot Flashes

Therapeutic Class
Adjunct anti-epileptic drugs

Pharmacology
Gabapen 100- Gabapentin is an anti-convulsant. It is a structural analog of gamma-amino-butyric-acid (GABA). All pharmacological actions following administration of Gabapentin are due to the activity of parent compound. Gabapentin binds with the alpha-2-delta subunit of voltage gated L-type Calcium channel, and inhibits branched chain amino acid transferase & probably inhibits neurotransmitter release of excitatory amino acid.

Dosage
Neuropathic pain: 300 mg on day-1, then 300 mg twice on day-2, then 300 mg thrice on day-3, then increase the dose according to response in steps of 300 mg daily to maximum 1800 mg daily in three divided doses.

Partial seizure/epilepsy: 300 mg on day-1, then 300 mg twice on day-2, then 300 mg thrice on day-3, then increase the dose according to response in steps of 300 mg daily to maximum 2400 mg daily in three divided doses.

In case of children:
For 3-12 years: 10 to 15 mg/kg, Incase of titration 25-35 mg/kg daily in 3 divided doses.
Maintenance dose is 900 mg daily (body weight 26-36 Kg) or 1.2 gm daily (body weight 37-50 Kg).

Administration
Gabapen 100- Gabapentin can be taken orally with or without food.

Interaction
Antacids may reduce the bioavailability of Gabapentin by up to 20%. Cimetidine may alter its reanal excretion. Gabapentin does not interact with other anti-epileptic drug or with oral contraceptive preparations.

Contraindications
Gabapen 100- Gabapentin is contraindicated in patients who have known hypersensitivity to the drug.

Side Effects
Generally Gabapentin is well tolerated but a few side effects like fatigue, dizziness , ataxia, weight gain, peripheral edema, dry mouth and somnolence, may occur. Rarely it may cause fulminate hepatic failure, or aplasticanemia.

Pregnancy & Lactation
Pregnancy: Gabapentin is a pregnancy category C drug; it should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Lactation: Gabapentin may be secreted through the breast milk like many other drugs , so it should be used in women who are nursing, only if the benefits clearly outweigh the risks.

Precautions
Patients should be instructed to take Gabapentin only as prescribed. While using Gabapentin patients should be instructed either not to drive a car or to operate other complex machinery until they have gained sufficient experiences about Gabapentin whether or not it affects their mental and/or motor performance adversely.

Use in Special Population
Use in Children: Safety and effectiveness of Gabapentin in the management of neuropathic pain in pediatric patients have not been established. Safety and effectiveness of Gabapentin in the management of seizures in pediatric patients below the age of 3 years have not been established.

Renal impaired patient: In case of renal impaired patient Gabapentin doses must be reduced :
CrCl >60 ml/min: 1200 mg/daily in 3 divided doses
CrCl 30-60 ml/min: 600 mg/daily in 2 divided doses
CrCl 15-30 ml/min: 300 mg/daily single dose
CrCl <15 ml/min: 150 mg/daily single dose or 300 mg/every alternate day
Heamodialysis: maximum 300 mg after each dialysis Gabapentin can be taken orally with or without food.

Storage Conditions
Tablets should be stored below 25° C and protected from light & moisture

If you need any assistance/consultation, please do not hesitate to contact us.

SKU: O-GAB-INC-100 Category:
Weight 0.1 g
Drug Manufacturer

Form Of Drug

Tablet

Generic Names

Based on 0 reviews

0.0 overall
0
0
0
0
0

Only logged in customers who have purchased this product may leave a review.

There are no reviews yet.