Indications for Cyclopan
Dicycloverine is indicated in:
Functional bowel/ irritable bowel syndrome
Urinary incontinence secondary to unstable detrusor muscle
Colicky abdominal pain
Anticholinergics (antimuscarinics)/ Anti-spasmodics
Cyclopan – Dicycloverine HCl relieves smooth muscle spasm in the GI and urinary tract. This effect is partly due to antimuscarinic action and partly direct action on the smooth muscle.
Dosage & Administration
Oral dosage forms-
Adults:10 to 20 mg three times a day.
Children >6 months of age: 5 to 10 mg three times a day.
Children <6 months of age: Dose must be determined by the doctor.
Oral dicycloverine Hydrochloride should be started as soon as possible
Intramuscular dosage form-
Adults: Intramuscular injection. Not for intravenous use. The recommended intramuscular dose is 80 mg daily (in 4 equally divided doses).
Intramuscular dosage form should not be used for periods longer than 1 or 2 days.
The following agents may increase certain actions or side-effects of Dicycloverine-antiarrhythmic agents, antihistamines, antipsychotic agents, benzodiazepines, MAO inhibitors, narcotic analgesics, nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants and other drugs having anticholinergic activity.
Cyclopan – Dicycloverine is contraindicated in:
Obstructive disease of the gastrointestinal tract
Severe ulcerative colitis
Unstable cardiovascular status in acute hemorrhage
Evidence of prior hypersensitivity to dicycloverine hydrochloride or other ingredients of this formulation
Infants less than 6 months of age
Insomnia, mydriasis, cycloplegia, increased ocular tension, urinary hesitancy, palpitations, dyspnea.
Pregnancy & Lactation
Pregnancy: Category B. Dicycloverine was neither teratogenic nor embryocidal in animal trial. It, like other drugs should be used during pregnancy only if clearly needed. There are no data on the secretion of this drug into breast milk. Dicycloverine should be used cautiously in case of lactating mother.
Use with caution in patients with autonomic neuropathy, hepatic or renal disease, ulcerative colitis, coronary heart disease, congestive heart failure, cardiac tachyarrhythmia, known or suspected prostatic hypertrophy.
Toxic reaction seldom occurs with dicycloverine. The signs and symptoms of overdosage are headache; nausea; vomiting; blurred vision; dilated pupils; hot, dry skin; dizziness; dryness of the mouth; difficulty in swallowing; and CNS stimulation.
Store below 30°C.
If you need any assistance/consultation, please do not hesitate to contact us.